How https://www.ceesdekker.net can Save You Time, Stress, and Money.
How https://www.ceesdekker.net can Save You Time, Stress, and Money.
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‘Indeed, that is about proper. I try to find a physical comprehension of Organic methods in the base-up way. I think you might distinguish a few lines of investigation in my team in the meanwhile. The first considerations chromosome framework: How does one obtain a metre-prolonged DNA polymer folded and organised in this kind of microscopic mobile? We have produced visualisation approaches that allow for us to study how, by way of example, SMC proteins loop DNA (movie on Youtube) so that you can Develop up chromosomes.
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For a individual, I possess the biblical assignment to examine and use every little thing in development for the good thing about my neighbour. I do not knowledge any conflict involving religion and science. Quite the opposite, my faith stimulates me to complete science, being open up-minded on the planet.’
Since 2000, Dekker has shifted the principle aim of his function in direction of biophysics where by he research the Houses of one biomolecules and cells utilizing the resources of nanotechnology. This variation of subject was pushed by his fascination for the exceptional operating of Organic molecular structures, in addition to through the very long-time period standpoint that many intriguing discoveries might be predicted During this field.[five] Current lines of study in his biophysics group are inside the regions of:[6]
This yielded a breakthrough. Within just only a few months, we have been in the position to evaluate transportation via a person solitary-walled carbon nanotube. Based upon low-temperature experiments by a brilliant PhD pupil in my group, Sander Tans (now a valued colleague and professor at Delft University of Know-how https://www.ceesdekker.net with the Energetic research lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes were being real quantum wires with pretty lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
The coiled-coil of your human Rad50 DNA maintenance protein includes certain segments of enhanced overall flexibility
Size Charge of person carbon nanotubes by nanostructuring While using the scanning tunneling microscope
Atomic drive microscopy displays that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative manner
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1). The present–voltage curves confirmed major modulations with gate voltage, even at home temperature, which was in line with band bending in the ~0.six eV bandgap semiconducting nanotube. These knowledge also showed that the conductance could be modulated by 6 orders of magnitude by switching the gate voltage. The results of the work — a space-temperature transistor created from an individual carbon nanotube molecule — have been revealed in Nature in Could 1998.
Screening pseudotopological and nontopological types for SMC-driven DNA loop extrusion towards roadblock-traversal experiments
Quite a few new phenomena have been discovered, and he and his investigate team proven a leading posture In this particular area of investigate. Dekker and his exploration group identified new physics of nanotubes as well as explored the feasibility of molecular electronics. In 1998, they ended up the very first to develop a transistor depending on only one nanotube molecule.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes
The biophysicist from Delft – who has become The most cited researchers within the Netherlands for years – usually takes his accountability to lead towards the explanation and popularisation of his do the job for the border of physics and biology really critically and regularly seems while in the media; if not to take a look at his operate, then about the relationship concerning science and his Christian religion.